Cardiovascular Diseases

Thrombophilia represents a predisposition to form clots inappropriately. It is caused by abnormalities in blood consistency, determined by modified levels and activity of coagulation factors that participate in the “coagulation cascade”.

Thrombotic events are increasingly recognized as a significant source of mortality and morbidity. Predisposition to form clots is a multifactorial disease: it derives from genetic factors, acquired changes in the clotting mechanism, or, more commonly, an interaction between genetic and acquired factors.

A significant proportion of the population has a detectable abnormality, but most of these only develop thrombosis in the presence of additional environmental risk factors. Clonit’s assays provide a complete coverage of frequent as well as rare mutations in genes related to the coagulation pathway reported to constitute risk factors for thrombophilia.

Brochure CVD Panel (download)