Mycobaterium avium complex

Duplicα RealTime Mycobacterium avium complex Detection Kit is an in vitro diagnostic test for the detection of Mycobacterium avium complex, by Real-Time PCR.

Overview

Mycobacterium avium-intracellulare complex (MAC) is the most common NonTuberculous Mycobacteria (NTM) pathogen. Previously, it was assumed that MAC colonized the lungs of patients with underlying disease. It is now recognized that this organism causes progressively destructive lung disease, sometimes over a period of years. Two patterns of pulmonary disease are seen in adult patients without HIV infection. Fibrocavitary disease that has clinical and radiologic similarities to tuberculosis is seen in patients with a history of tobacco and/or alcohol abuse, usually male patients with underlying COPD, bronchiectasis, silicosis, previously active tuberculosis, chronic aspiration, or immunosuppression. More recently, it has been recognized that MAC causes nodular bronchiectasis, a condition seen primarily in elderly women without an obvious immunodeficiency disorder; if untreated, the condition can progress to respiratory failure and death.

Targets:

16S-23S rRNA gene
Internal Control (IC)

Diagnostic samples:

Respiratory spicemens

Real-Time PCR instruments:

Compatible with the most common Real-Time PCR Systems

DNA Extraction:

Compatible with the most common DNA Extraction and Purification Systems